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Injectable Skin Treatment · Chichester

Polynucleotide Skin Treatments in Chichester

Consultation-led polynucleotide (PDRN) treatment with Dr Etienne Raffner. Book a consultation to discuss whether it may be suitable for your skin.

5.0 Google· 51 reviews

"I've had several appointments with Dr Etienne Raffner now. He's a great doctor as he always listens to my concerns and gives plenty of advice and encouragement."

— Google Review

"Dr Raffner is an incredibly skilled and knowledgeable surgeon. His attention to detail and care for his patients is second to none."

— Google Review

"Absolutely fantastic experience with Dr Raffner. He made me feel completely at ease and the results are beautiful and natural."

— Google Review

"Dr Etienne is so professional and reassuring. He took the time to explain everything in detail. I couldn't be happier with the results."

— Google Review

"Outstanding care from Dr Raffner. You can really tell he has a surgical background — so precise and thorough. Highly recommend."

— Google Review

"The most natural-looking results I've ever had. Dr Raffner's medical expertise really shows. He has a wonderful, calming manner."

— Google Review

"I felt completely confident in Dr Raffner's hands. His knowledge as a maxillofacial surgeon makes such a difference to the quality of results."

— Google Review

"I've had several appointments with Dr Etienne Raffner now. He's a great doctor as he always listens to my concerns and gives plenty of advice and encouragement."

— Google Review

"Dr Raffner is an incredibly skilled and knowledgeable surgeon. His attention to detail and care for his patients is second to none."

— Google Review

"Absolutely fantastic experience with Dr Raffner. He made me feel completely at ease and the results are beautiful and natural."

— Google Review

"Dr Etienne is so professional and reassuring. He took the time to explain everything in detail. I couldn't be happier with the results."

— Google Review

"Outstanding care from Dr Raffner. You can really tell he has a surgical background — so precise and thorough. Highly recommend."

— Google Review

"The most natural-looking results I've ever had. Dr Raffner's medical expertise really shows. He has a wonderful, calming manner."

— Google Review

"I felt completely confident in Dr Raffner's hands. His knowledge as a maxillofacial surgeon makes such a difference to the quality of results."

— Google Review

What Are Polynucleotides?

Polynucleotides are a category of injectable skin treatment based on purified DNA fragments. The form most commonly used in aesthetic medicine is known as PDRN (polydeoxyribonucleotide), and the two terms are often used interchangeably. Unlike dermal fillers, polynucleotides do not add volume — their intended aim is to support skin quality and appearance.

At Oving Medical Clinic in Chichester, polynucleotide treatment is consultation-led and provided by Dr Etienne Raffner. Every patient is assessed individually before any treatment is recommended.

Is the Product Fish-Derived?

Yes. The polynucleotide products used at this clinic are derived from purified salmon DNA. The DNA fragments undergo extensive purification during manufacture. If you have a known fish allergy, it is important to mention this at your consultation so that suitability can be properly assessed.

Treatment Areas

Face (including under-eye area)
Neck
Décolletage
Hands

Skin Concerns the Consultation May Consider

Skin dullness or uneven texture
Fine lines and crepiness
Under-eye hollows or dark circles
Sun-related changes in skin appearance
Acne scarring
General skin quality maintenance

Whether polynucleotide treatment is appropriate for your concern is assessed at consultation. Dr Raffner may also discuss alternative or combined approaches where they may be more suitable.

Polynucleotides vs Fillers vs Skin Boosters

Dermal fillers

Use hyaluronic acid gel to add volume, restore contours and soften deeper lines.

Skin boosters

Deliver hyaluronic acid to hydrate the skin and support skin quality.

Polynucleotides (PDRN)

DNA-based; do not add volume. Intended to support skin quality and appearance rather than to plump or fill.

Allergy & Suitability Considerations

Polynucleotide treatment is not suitable for everyone. Suitability is assessed at consultation. Considerations include:

  • Known fish allergy (the product is salmon-derived)
  • Pregnancy or breastfeeding
  • Active skin infection or inflammation in the treatment area
  • Certain autoimmune or inflammatory conditions
  • Current medication that may affect treatment or healing

Dr Raffner reviews your medical history before advising whether the treatment is appropriate for you.

Consultation & Treatment Process

1

Consultation

Dr Raffner assesses your skin, discusses your concerns and goals, reviews your medical history and advises whether polynucleotide treatment is appropriate — or whether an alternative or combined approach may be more suitable. There is no obligation to proceed.

2

Treatment

After applying a topical numbing cream, the product is injected through a series of small injections across the treatment area. A session typically takes 20–30 minutes.

Number of Appointments

A course of 2–3 treatments, spaced 2–4 weeks apart, is commonly discussed at consultation. Some patients consider maintenance treatments thereafter. Your individual plan is agreed with Dr Raffner based on your skin and goals.

Downtime & Aftercare

Downtime is minimal. Mild redness, swelling or small marks at the injection points may be visible for 24–48 hours. Most patients return to normal activities the same day. Detailed aftercare advice is provided after treatment.

Risks & Limitations

As with any injectable treatment, polynucleotide treatment carries potential risks including bruising, swelling, redness, tenderness and, less commonly, infection or allergic reaction. Results vary between individuals and are not guaranteed.

Polynucleotide treatment is not an alternative to surgery and will not reverse the ageing process. A full discussion of risks and what to realistically expect takes place at your consultation.

Results & How Long Effects May Last

Some patients notice an improvement in skin hydration after the first treatment, with changes in texture and tone developing gradually over the following weeks. Individual responses vary and results cannot be guaranteed.

Effects are not permanent. Maintenance treatments are commonly discussed to help sustain any improvement. The duration of any visible effect varies between individuals.

Prices

Plinest — Single treatment

£250

Plinest — 3 treatment package (Face, Eyes, Neck or Décolletage)

£675

Newest — Single treatment

£275

Newest — 3 treatment package

£700

Hand rejuvenation

From £399

Final pricing confirmed at consultation based on your individual needs.

Product Used

The polynucleotide products currently used at this clinic are Plinest and Newest (Mastelli). Product selection is confirmed at your consultation based on your individual needs.

Your Practitioner

Dr Etienne Raffner is a Specialist Grade Maxillofacial & Oral Surgeon with over a decade of clinical experience. He is a core member of the Kent & Sussex Skin Cancer Multidisciplinary Team. His surgical background informs a careful, assessment-led approach to every treatment.

Read more about Dr Raffner

Frequently Asked Questions

Related Treatments

Book a consultation to find out more

Dr Raffner will assess your skin and advise whether polynucleotide treatment is right for you.

Book a Consultation